With Iowa suffering key losses to the portal, Missouri should have the edge as it seeks its second consecutive 10-win season.

Our Iowa vs. Missouri prediction for the Music City Bowl, part of our college bowl game predictions this week, sees a largely intact Tigers' offense as the difference in a matchup between Midwestern opponents.

Our college football bowl game opt-out tracker has you covered with the latest opt-out news and the impact on the college bowl game odds. 

Iowa vs. Missouri prediction & best pick: Music City Bowl

College football picks based on the odds from our best college football betting sites. 원타임 카지노 데일리 보너스 subject to change.

• Against the spread pick: Missouri -2.5 () vs. Iowa ⭐⭐⭐⭐
• My best pick: Over 40 (-110 via Caesars) ⭐⭐⭐⭐⭐

Iowa vs. Missouri ATS prediction

Missouri to cover the spread: -2.5 ⭐⭐⭐⭐

Best odds: -110 via Caesars | Implied probability: 52.38%

Missouri loses NFL prospects WR Luther Burden III and OL Armond Membou as opt-outs for this matchup, but the Tigers come into the Music City Bowl with their starting quarterback, running back, and another top receiving threat intact.

Hawkeyes’ heartbeat opt outs

Iowa cannot say the same after the heartbeat of the offense, 1,500-yard rusher Johnson opted out.

Without Johnson, Iowa’s offense, which ranks 69th in adjusted efficiency, could be underwhelming against Mizzou’s 19th-ranked adjusted defensive efficiency. Only LB Chuck Hicks opted out among Missouri’s primary defensive contributors.

As of this writing on Saturday afternoon, a substantial edge can be gained by playing this wager at Caesars for the spread at Missouri -2.5 with -110 odds. FanDuel has the same spread with odds at -122, with all other sportsbooks featuring the Tigers at -3.

Iowa vs. Missouri best pick

Our NEW college football player prop odds tool can help you find the best odds on any market across legal sportsbooks in your area!

Over 40 points ⭐⭐⭐⭐⭐

Best odds: -110 via Caesars | Implied probability: 52.38%

The Tigers and Hawkeyes combined to score an average of 54.0 points per game this season, which would blow this total out of the water. Even the combination of their stout scoring defenses (40.5) lands slightly above this meager number.

Not so fast on Iowa Unders anymore?

It’s been the season from the ‘Upside Down’ as our best sportsbooks have overcorrected for Iowa’s traditionally woeful offense when setting totals.

The Hawkeyes had nine of their 12 games go Over this season, with only three finishing below 40 points.

Missouri also saw only three of its games dip below 40 total points during the season and will have the trio of QB Brady Cook, RB Nate Noel and WR Theo Wease arguably as healthy as they've been at any juncture.

Listing the total at 40, Caesars is a great spot for Over bettors to grab it as opposed to the 40.5 number from BetMGM, FanDuel and DraftKings.

Iowa vs. Missouri odds

See all of this week's college football odds and NCAAF scores.

Iowa vs. Missouri live odds

Iowa vs. Missouri opening odds:

• Iowa: +2.5 (-110)
• Missouri: -2.5 (-110)

Iowa vs. Missouri injuries

Music City Bowl game info

• When: Monday, Dec. 30
• Kickoff: 2:30 p.m. ET
• Where: Nissan Stadium (Nashville, Tenn.)
• How to watch: ESPN
• Weather: 60 degrees, 0% chance of precipitation, wind 6 mph SSW
• Favorite: Missouri -2.5 (-110 via Caesars)

College football betting odds pages

Here are our best college football betting sites:

• Caesars Promo Code: SBRBONUSDYW | Read our Caesars Review
• BetMGM Bonus Code: SBRBONUS | Read our BetMGM Review
• bet365 Bonus Code: SBRBONUS | Read our bet365 Review
• FanDuel Promo Code | Read our FanDuel Review
• DraftKings Promo Code | Read our DraftKings Review

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